2012.6
About Instruments Today No. 188
Photonics
Optical Distribution Meter by Screen Image Synthesis System [ 下載 PDF ]
Yeh-Wei Yu, Wei-Hsin Chen, Yen-Lin Chen, Hen-Xiang Chen, Ching-Cherng Sun
Light-emitting diodes are common light sources in modern lighting. The optical distribution of an LED package and the bidirectional scattering distribution function (BSDF) of diffusing optical components are important factors in lighting design. This paper proposes an innovative method of measuring both the optical distribution of LEDs and BSDF quickly. The proposed method uses a 2-D screen and a camera to capture the illumination on a screen, and acquires the whole-field optical distribution by synthesizing the images on the screen in different angles. This paper presents theoretical calculations and experimental results demonstrating the construction of the BSDF.
"Artifi cial, Targeted, Light-Activated Nanoscissor for Sequence Selective Gene Scission" [ 下載 PDF ]
Ying-Ying Li, Tsung-Lin Tsai, Dar-Bin Shieh
The discovery of restriction enzyme and ligase have brought about a revolution in biomedical technology industry in the 20th century. Through the completion of the Human Genome Project and whole genome decoding of more organism, a tremendous opportunity for advanced applications in food industry, biofuel and fighting human diseases has been opened. This technology developed an artificial targeted, light-activated nanoscissor (ATLANS) for advanced in-cell photonic manipulation of target gene scission and silencing through formation of targeted DNA triplex in the nucleus and double strand DNA scission at predesigned site through photonic activation in the visible wavelength photon energy. The technology has been successfully developed to remove green fluorescent gene in cancer cells. When target to cancer drug resistant gene, ATLANS may effectively decrease chemotherapeutic dosage and thus reduce systemic side effects while increase therapeutic efficacy. The technology could be applied to clinical disease management of cancer, infectious disease and genetic diseases in the future development.
Three-Dimensional Optical Imaging Systems [ 下載 PDF ]
Cheng-Chung Lee, Kai-Wu, Jui-Chang Tsai, Yuan Luo
Optical imaging plays a critical role for various areas. The first optical microscopic imaging system was developed in the 17th century by Anton van Leeuwenhoek, who is known as the father of microscopy. Since then, much effort has been involved in developing high-speed three-dimensional (3D) imaging systems for a variety of applications. Ideally, optical imaging systems would provide 3D images, enabling characterization of a volume of tissue. However, all these systems have complex mechanical designs, requiring scanning in two lateral dimensions, or depth focusing. The complex designs increase device cost, reduce robustness, and increase the complexity. In this Article, we review our novel imaging methods including volume holographic imaging and polarized interferometry to acquire high-resolution 3D images of an object with no need of scanning.
Optimization of Secondary Optical Lens Design for LED Lighting [ 下載 PDF ]
Chi-Feng Lin, Yu-Bin Fang, Po-Hua Yang
In this study, pattern search was used to optimize the secondary optical lens for LED lighting. Under the assumption of point light source, the lens with uniform illumination can be constructed by using energy mapping relationship and Snell's law. However, the non-uniform illumination is found in the luminaire designed with LED light source due to the size effect. Although larger LED lens can eliminate the size effect, the drawbacks are complex mechanical assembly of luminaire and higher production cost. Therefore, the pattern search was implemented to adjust the designed parameters of lens for keeping a uniform illumination without increasing the size of lens, so that the size effect of LED is less obvious.
The Software Module Development of Fast Data Calculation in Ellipsometry for Single Layer Film [ 下載 PDF ]
Yu-Sung Hsieh, Yu-Jen Lu, Yi-San Chang
Ellipsometry is a special technology of thin film characteristics measurement and can help obtain several key parameters of the sample: film thickness, refractive index, extinction coefficient, surface roughness and so on. In this study, some required items of thin film thickness calculation including math algorithm, software framework and user interface design are discussed here and the results show it'll get high calculation rate of thin film thickness and avoid appearing multiple solutions using algebraic analytic model compared with standard film sample.
A Simple Smart Phone Radionuclide Survey Meter [ 下載 PDF ]
Hsun-Hua Tseng
Experiences gained from Japan Fukushima nuclear accidents have told us that conventional SOPs are not applicable to urgent, large area radioactive isotopes survey. Although we can count on mobile radiological laboratories which are delivered with sophisticated measurement and data manipulation equipments, however both their quantity and viability are highly limited and they are still far from enough under emergent conditions. The Institute of Nuclear Energy Research has developed a simple smart phone radionuclide survey meter based on her unique pulse analysis chip. Thanks to great technology progress on massive low cost smart phone and NaI (Tl) scintillation detectors, we may get all necessary tasks be done on site simultaneously such as, multi-channel analysis, nuclide identifi cation, activity measurements, GPS positioning, and long range wireless transmission required for large area survey simply by finger tip on smart phone touch screen of this light weight equipment.
Room Environment Monitoring Based on Smart Phone [ 下載 PDF ]
Shih-Chieh Chou, Ping-Hung Lin, Tai-Shan Liao, Fong-Zhi Chen
With the rapid development of information systems and its wide adoption in organizations, the server room of these systems has become increasingly important to an organization's technical operation. The popularity of smart phones in the past few years has given mobile phones a whole new defi nition in means of communication. Phones are no longer the tools that merely make/receive calls. In this article we discussed about the connection between information systems and mobile phones, and in concrete explanation about how mobile phones were utilized as realtime monitoring and warning systems on the change of humidity, air-condition, water leakage, fire, etc. in the server room for the sake of security control.
Multi-Functional DEP Chip System for Diagnosis of Different-Grade Bladder Cancer Cells [ 下載 PDF ]
Yao-Wei Huang, You-Ming Hsu, Yao-Tung Wu, Cheng-Hsin Chuang
In this work, a dielectrophoretic (DEP) chip with multi-layer electrodes and a micro-cavity array was developed for programmable manipulations and impedance measurement of bladder cancer cells. Impedance sensing of single cells could be performed as follows: Firstly, cells were trapped in a micro-cavity array by negative DEP force constructed by top and middle electrodes; then, the impedance measurement for discrimination of different grades of bladder cancer cells was accomplished by the middle and bottom electrodes. After impedance sensing, the individual releasing of trapped cells was achieved by negative DEP force using top and bottom electrodes in order to collect the identified cells once more. In the experimental results, the capability of electrical manipulation successfully demonstrated by human bladder cancer cells (TSGH8301 and T24). Consequently, the DEP chip provides an excellent platform technology for lab-on-a-chip (LOC) or micro-total-analysis-system (micro TAS).
Fabrication of Nanocone Subwavelength Antirefl ection Structures on Quartz Substrates [ 下載 PDF ]
Yu-Hsiang Tang, Mao-Jung Huang, Jien-Yin Su, Ming-Hua Shiao
This study combined self-assembled nanosphere lithography (SANL) and inductively coupled plasma reactive ion etching (ICP-RIE) for fabricating orderly arranged nanocone arrays on a quartz substrate. We established a simple process for successfully fabricating subwavelength structure (SWS) on glass substrate, achieving broadband anti-reflection (AR) and increasing the transmittance of incident light across the quartz glass. This novel process arranged a monolayer of nanospheres onto 2 × 2 cm2 test specimen. In addition, we evaluated various etching times of ICP-RIE for producing SWS surfaces, which resulted in various specific surface areas for the quartz surfaces. Smoothly tapered SWS surfaces with a width of 108 nm and a height of 190 nm could be produced on quartz wafer. This fabricated SWS decreased the surface reflectance less than 6.75% in the visible light spectrum.