2004.10
About Instruments Today No. 142
Automatic Electro-Optical Inspection
Multi-Functional Optical Biochip System — Opto- BioMorphin [ 下載 PDF ]
Wei-Liang Hsu, Shu-Sheng Lee, Chih-Kung Lee
OBMorph is a multi-functional optical biochip system. This biosensor is developed by integrating ellipsometry and SPR detection techniques, which adopted a flow-injection system to supply biosamples to biochip. The other important function of this biosensor is to observe SPR phenomenon by using the ellipsometric configuration. By using this method, the SPR resolution could be significantly enhanced, and the characteristics of ellipsometry give detailed information for bio-tech analysis. Information such as film thickness, physical parameters, concentration, mass, density, kinetic constants, binding specificity, etc. can all be retrieved. In summary, OBMorph could serve both as a research and development tool as well as a manufacturing tool in biomedical area.
Automatic Inspection of Optical Switch [ 下載 PDF ]
Kuang-Chao Fan, Wu-Lang Lin, Hung-Yu Wang
In recent years, the requirement of communication bandwidth increases rapidly. The optical-fiber communications industry will be the vigorous new industry in the future. The optical switch component plays an extremely important role in the optical-fiber communications. Most of the optical communication components are, however, aligned and assembled manually. They are unable to mass product automatically. For this reason, this article will introduce the latest research of the optical switch automation assembly system and design the mechanical type Fiber-To-Fiber optical switch. By the micro three-dimension measurement and CCD image processing alignment techniques, we will develop automatic coupling of optical fiber and assembly technique to fabricate the optical switch conforming to the international Bellcore testing standards.
The Design and Applications of Automatic Optical Inspection System in the LCD Production Line [ 下載 PDF ]
Chern-Sheng Lin
The series of LCD modules covers each of the procedures: baking, curing, rubbing, dry cleaning, combination rubbing and dry cleaning, spacer spraying, gasket seal printing and dispensing, combination alignment, assembly, and liquid crystal filling. The applications of the automatic optical inspection (AOI) system in these procedures will bring higher quality and more efficiency to the LCD production line. The AOI system used discriminate mask, counting mask, and a fast processing algorithm for counting spacers in a liquid crystal display plate. An AOI equipment in LCD positioning system was implemented for LCD testing and gluing. In LCD backlight inspection, a wrapping algorithm was presented in the searching and statistic process of bright spot. A method for estimating the gap of LCD glasses using a photoelectric measuring system was presented in the final.
Optical Micro-to-Nanoscale Surface Profilometry [ 下載 PDF ]
Hua-Chen Hsu, Chung-Fan Tu, Calvin C. Chang
Throughout the manufacturing processes in many prominent industries, the micro-to-nanoscale surface profilometry is frequently resorted to for the assurance of the producing quality, so that manufacturing flaws or defects can be noticed and rectified and the semi-finished product can be reworked or abandoned before any unnecessary post-process get executed. With this in-process inspection, the manufacturing process can be more efficient and the producing cost can be further reduced. In this article, two types of optical micro-to-nanoscale surface profilometry are presented and their applications are briefed.
The Development of Hyperspectral Imager and Images Market Forecast [ 下載 PDF ]
Long-Jeng Lee
With rich geometric and spectral information, applications of hyperspectral images have been highly expected; they have been mainly applied to remote sensing and microscopy presently. The major application to remote sensing is focused on the earth resource investigation and environmental monitoring, such as precision agriculture, mineralogy, forest, ecology, and water quality monitoring, while the application to microscopy is on bio-fluorescence study and spectral images of chemical composition. Development of hyperspectral instruments and image application will be introduced, and the future market forecast will be discussed.
An Introduction to Mass Spectrometry of Single Bacterial Whole Cells [ 下載 PDF ]
Wen-Ping Peng, Yi-Chang Yang, Ming-Wei Kang, Hao-Wei Kao, Yuan T. Lee, Huan-Cheng Chang
Measuring masses of single intact microorganisms represent a challenge to modern biotechnology. To take on this challenge, we have developed a novel method to precisely measure the masses of single bacterial whole cells using a quadrupole ion trap as an electrodynamic balance. The bacterial cells were introduced into the ion trap by matrix-assisted laser desorption/ionization, confined in space by audio-frequency ac fields, and detected by elastic light scattering. Mass measurement accuracy approaching 0.1% was achieved for Escherichia coli K-12, with a mass distribution of (3% form 60 repetitive measurements of the particles and their clusters. This is the first high-precision mass measurement reported to date for any intact microorganisms with masses greater than 1 × 1010 Da. The method opens new avenues for high-precision mass measurement microbial particles and offers an alternative approach for rapid identification of microorganisms by mass spectrometry.
A New Economic Method to Generate Fast High Voltage Pulse [ 下載 PDF ]
Jieh-Wen Tsung, Jim Jr-Min Lin
A fast high voltage pulse generating device, which is capable to replace expensive commercial pulse generators, is presented. In this device, a coaxial cable is charged to a high voltage, and then the charges are released to an impedance-matched load through a fast transistor switch. Because charges are transmitted with constant speed in transmission line, a square wave can be generated. Also, the pulse width can be precisely controlled by the length of the cable. The testing results show that the highest pulses height is 1380 V, and the shortest pulse width is less than 20 ns. Thus, the pulse generated by this method has extremely high instantaneous power. The pulses are jitter-free, and the waveforms of the pulses approach to an ideal square wave, too. This device is simple and economic, but the quality of the output pulse is not worse than very expensive instruments. Hence, we believe that this design will have many applications.
MEMS Technology for Space Applications [ 下載 PDF ]
Chien-Hung Ho
This article presents an overview of MEMS technology for space applications. Since the launch costs of space missions have been very expensive for the past three decades, it is gradually difficult to obtain extra support for the flight of large-scale vehicles. Currently, many avenues are adopted to find out the possible solution for saving the expenditure on space exploration. One of the approaches that may be considerably effective is the miniaturization of a spacecraft. In order to accommodate the size and mass limitations, MEMS technology provides an essential machining tool for the fabrication of a micro- or nano-based spacecraft, and therefore, gives the key to mission cost reductions. However, being a new technology, MEMS devices are still immature for common use in space. To overcome this problem, a better way is to establish an integral flight test and demonstration, which allows this technology to mature as soon as possible.
The Principle and Applications of Liquid Chromatography / Atmospheric-Pressure Photoionization Mass Spectrometry [ 下載 PDF ]
Han-Wen Kuo, Wang-Hsien Ding
Atmospheric-pressure photoionization (APPI) is a newly developed ionization method for liquid chromatography/mass spectrometry (LC/MS). This method not only extends the applications of LC/MS, but also reduces the interference of matrix effect for trace analysis due to its specific ionization mechanism. This article is to introduce its development, ionization principle, and many applications for various compounds.
